Hyaline membrane disease in relation to fibrinolytic activity

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Hyaline Membrane Disease in Relation to Fibrinolytic Activity.

There are several points of interest about hyaline membrane disease in relation to any discussion of fibrinolytic activity. In paediatrics hyaline membrane disease is a persisting cause of mortality. Between 40% and 60% of premature infants dying in the first five days of life are said to die of this condition. The diagnosis falls to the pathologist who examines the lungs after death, for durin...

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Prevention of Hyaline Membrane Disease

The high mortality of respiratory distress syndrome in premature infants and the relative ineffectiveness of treatment' make two recent reports of special interest. They are clinical studies2 3 which attempt to clarify the role of corticosteroids in prevention and treatment. New forms of treatment for this puzzling disorder have sometimes been introduced without adequate trials, so that it is h...

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Assisted Ventilation in Terminal Hyaline Membrane Disease.

Goldsmith and Karotkin' researched the history of assisted ventilation and found that a record of mouth to mouth methods goes back to Old Testament times, and Hippocrates himself reported his experience with tracheal intubation to support pulmonary function. These skills were ignored for about 2000 years as it was not until the 16th century that attention was again paid to this subject when bel...

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Artificial surfactant therapy in hyaline-membrane disease.

Ten preterm infants severely ill with hyaline-membrane disease (HMD) were given artificial surfactant endotracheally. Oxygenation and alveolar-arterial oxygen gradients improved, the levels of inspired oxygen and peak respirator pressure could be reduced, and many of the radiological abnormalities resolved. Acidosis and systemic hypotension were also reversed. In nine infants a patent ductus ar...

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Hyaline membrane disease. II. Lung lecithin.

Boughton, K., Gandy, G., and Gairdner, D. (1970). Archives of Disease in Childhood, 45, 311. Hyaline membrane disease. H: Lung lecithin. The lecithin content of lung, together with its surface tension properties, were determined in 34 stillbirths, and 61 neonatal deaths. Lecithin content ranged widely from 1-5 to 18 6% of dry lung tissue. In 24 cases the 'palmitic-lecithin' was also measured; i...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1964

ISSN: 0021-9746

DOI: 10.1136/jcp.17.3.345